2 Reasons This Will Be Gilead’s Year, Says Morgan Stanley
Two things will happen this year that will lift investors’ esteem of Gilead Sciences, says Morgan Stanley in an upgrade note Tuesday. A successful breast-cancer study could open a multibillion-dollar market for Gilead’s Trodelvy antibody. And a long-acting drug could restore growth to the company’s HIV treatment franchise.
Analyst Matthew Harrison raised his rating on the stock from a Hold to a Buy, setting a price target of $83. The upgrade helped lift Gilead (ticker: GILD) 5.9% in recent trading, to $67.05. If Harrison proves right, there’s still more than 20% upside to the stock.
Gilead received Trodelvy with its 2020 acquisition of Immunomedics. The product links a tumor-targeting antibody with an anticancer drug payload. Before the end of the year, the company expects to report how long the treatment stopped cancer progression in a Phase 3 trial against the metastatic breast cancers of the HR-positive/HER2-negative category, which afflicts about 120,000 U.S. women.
Early studies were encouraging, and Harrison gives the Phase 3 study a 75% likelihood of success. The resulting sales could add $1.8 billion to Gilead’s annual revenue.
The second big catalyst he expects this year will be for the drug lenacapavir, which targets the capsid protein in HIV. The long-acting drug can be given as an injection just twice a year, or as a pill once a week. Gilead plans trials that test ienacapavir in combination with long-acting antiviral drugs of its own, or from another drugmaker. The novel drug islatravir from Merck (MRK) would be a good choice, says Harrison.
The resulting HIV combination treatment could prove highly effective and worth $9 billion in annual revenue, Harrison estimates. Even if Gilead shares profits with a partner, the earnings could add more than $15 to Gilead’s stock price, he says.
Write to Bill Alpert at [email protected]